By Moore R. L.
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38 Autism Spectrum Disorders: The Role of Genetics in Diagnosis and Treatment RS is one of the better examples of an autism-related disorder with a proven genetic pathophysiology. , characteristic stereotypy such as handwringing at chest level and a relative maintenance of eye contact), research in RS could nevertheless contribute to a better understanding of involvement of central nervous system dysfunctions in autism. X-chromosome MECP2-gene a Mutations (~5%) 5’UTR b 3’UTR Exon 1 Exon 2 Exon 3 Exon 4 Mutations (>55%) Small deletions (>10%) Fig.
One year later, the Austrian pediatrician Hans Asperger reported comparable findings under the title ‘Die ‘Autistischen Psychopathen’ in Kindesalter’. , ‘autistic aloneness’). Up until the beginning of the 1960s, under the influence of the then prevalent psychodynamic theories, autism was largely attributed to family and environmental factors. Rutter (1968) placed autism in a different perspective and demarcated the phenotypical presentation of both early infantile autism and schizophrenia from their biological underpinnings.
Clubley, E. (2001). The AutismSpectrum Quotient (AQ): Evidence from Asperger Syndrome/high-functioning autism, males and females, scientists and mathematicians. , & Lord, C. (2006). Association between restricted and repetitive behaviors and NVIQ in children with autism spectrum disorders. Child Neuropsychology, 12 (4-5): 247-67. , & Holmes, C. (2008). Characteristics of children with autism spectrum disorders who received services through community mental health centers. Autism. 12(1):65-82.
Concerning the Prime Parts of Certain Continua Which Separate the Plane by Moore R. L.