Health Publica Icon Health Publications's Cervical Cancer - A Medical Dictionary, Bibliography, and PDF

By Health Publica Icon Health Publications

ISBN-10: 0585494193

ISBN-13: 9780585494197

ISBN-10: 0597838178

ISBN-13: 9780597838170

This can be a 3-in-1 reference e-book. It supplies an entire scientific dictionary masking 1000's of phrases and expressions in terms of cervical melanoma. It additionally supplies broad lists of bibliographic citations. ultimately, it offers details to clients on the right way to replace their wisdom utilizing quite a few net assets. The ebook is designed for physicians, scientific scholars getting ready for Board examinations, scientific researchers, and sufferers who are looking to get to grips with learn devoted to cervical melanoma. in the event that your time is efficacious, this e-book is for you. First, you won't waste time looking out the net whereas lacking loads of suitable details. moment, the booklet additionally saves you time indexing and defining entries. ultimately, you won't waste time and cash printing enormous quantities of web content.

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365 Hope St Providence, Ri 02906 Timing: Fiscal Year 2001; Project Start 01-SEP-2001; Project End 31-AUG-2003 Summary: Human Papilloma Virus (HPV) types 16 and 18 are detected in roughly 70% of all invasive cervical tumors. Among cytologically normal women, detection of HPV infection by PCR has been shown to increase the subsequent risk of cervical cytologic abnormalities by 12 fold, suggesting that effective vaccines (preventive/therapeutic) for HPV infection would be a useful medical advance in the battle against this cancer.

5. Dermal infiltration by mast cells in epidermal dysplasias, and their role in malignant progression. The long term goal is to define the pathways to epidermal and cervical cancer in mice expressing oncogenes implicated in a relevant human cancer, identifying the critical cellular and molecular parameters governing progression, and eventually utilizing the knowledge of mechanism to design therapeutic and preventative interventions that can be evaluated in this preclinical model of human carcinogenesis.

We have developed an animal model in which one co-factor associated with HPV neoplasia, chronic estrogen treatment, induces multi-step cervical and vaginal carcinogenesis in transgenic mice expressing the entire early region of HPV16 under control of the human keratin-14 promoter (K14-HPV16 transgenic mice). We will investigate the hypothesis that the cooperation between estrogens and the oncogenes of HPV is a major determinant of cervical carcinogenesis. The specific aims are: 1. Examine whether cervical neoplasia is decreased by decreasing doses of estrogen or by the addition of progesterone, and determine whether carcinogenesis persist after the cessation of estrogen treatment.

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Cervical Cancer - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Health Publica Icon Health Publications


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