New PDF release: Cell Cycle Checkpoints and Cancer

By Mikhail V. Blagosklonny

ISBN-10: 1587060671

ISBN-13: 9781587060670

Cellphone Cycle Checkpoints and melanoma is ready mechanisms of standard and melanoma phone biking, checkpoint keep an eye on, and the hyperlink of mitogenic signalling and mobile cycle equipment. Checkpoint mechanisms from yeast to guy are addressed to permit a entire realizing of the mobile cycle. purposes to present and destiny anticancer treatments are mentioned.

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Proc Natl Acad Sci USA 1985; 82:7414-7418. 5. Ihle JN, Pepersack L, Rebar L. Regulation of T-cell differentiation: In vitro induction of 20α-hydroxysteroid dehydrogenase in splenic lymphocytes from athymic mice by a unique lymphokine. J Immunol 1981; 126:2184-2189. 6. Schrader JW, Lewis SJ, Clark-Lewis I, et al. The persisting (P) cell: Histamine content, regulation by a T cell-derived factor, origin from a bone marrow precursor, and relationship to mast cells. Proc Natl Acad Sci USA 1981; 78:323-327.

79. Azimi N, Jacobson S, Leist T et al. Involvement of IL-15 in the pathogenesis of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis: Implications for therapy with a monoclonal antibody directed to the IL-2/15R beta receptor. J Immunol 1999; 163:4064-4072. 80. McCubrey JA, Steelman LS, Hoyle PA et al. Differential abilities of activated Raf oncoproteins to abrogate cytokine-dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells.

Cockerill PN, Shannon MF, Bert AG et al. The granulocyte-macrophage colony-stimulating factor/ interleukin-3 locus is regulated by an inducible cyclosporin A-sensitive enhancer. Proc Natl Acad Sci USA 1993; 90:2466-2470. 40. Uchida H, Downing JR, Miyazaki Y et al. Three distinct domains in TEL-AML1 are required for transcriptional repression of the IL-3 promoter. Oncogene 1999; 18:1015-1022. 41. Mao S, Frank RC, Zhang J et al. Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias.

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Cell Cycle Checkpoints and Cancer by Mikhail V. Blagosklonny

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Categories: Oncology