By Edward B Stelow MD, Stacey Mills
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Extra resources for Biopsy Interpretation of the Upper Aerodigestive Tract and Ear
J Laryngol Otol. 1963;77:635-647. 5. Einhorn J, Wersall J. Incidence of oral carcinoma in patients with leukoplakia of the oral mucosa. Cancer. 1967;20:2189-2193. 6. Pindborg JJ, Jolst O, Renstrup G, Roed-Petersen B. Studies in oral leukoplakia: a preliminary report on the period prevalence of malignant transformation in leukoplakia based on a follow-up study of 248 patients. J Am Dent Assoc. 1968;76:767-771. 42 –––––– BIOPSY INTERPRETATION OF THE UPPER AERODIGESTIVE TRACT AND EAR 7. Silverman S Jr.
For this reason, clinical follow-up and complete excision are recommended for any adult with a solitary papillary lesion that shows any degree of atypia. Verrucous carcinomas will not, by definition, show more than mild cytologic atypia and should show keratinization. They should not be diagnosed if the base of the lesion cannot be assessed on biopsy to verify destructive invasion. 10,11 They are classified according to their growth pattern (exophytic/fungiform vs. endophytic/inverted) and by their epithelial cell type (squamous vs.
Laryngeal keratosis and subsequent carcinoma. Head Neck Surg. 1979;1:386-391. 14. Henry RC. The transformation of laryngeal leucoplakia to cancer. J Laryngol Otol. 1979;93:447-459. 15. Crissman JD, Zarbo RJ. Dysplasia, in situ carcinoma, and progression to invasive squamous cell carcinoma of the upper aerodigestive tract. Am J Surg Pathol. 1989;13(suppl 1):5-16. 16. Lumerman H, Freedman P, Kerpel S. Oral epithelial dysplasia and the development of invasive squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod.
Biopsy Interpretation of the Upper Aerodigestive Tract and Ear by Edward B Stelow MD, Stacey Mills