Atopic Dermatitis and Eczematous Disorders by Donald Rudikoff, Steven R Cohen, Noah Scheinfeld PDF

By Donald Rudikoff, Steven R Cohen, Noah Scheinfeld

ISBN-10: 1306410304

ISBN-13: 9781306410304

ISBN-10: 1840761954

ISBN-13: 9781840761955

ISBN-10: 1840766530

ISBN-13: 9781840766530

It really is predicted that round 15% of the inhabitants be afflicted by atopic dermatitis or eczematous issues sooner or later of their lifetime, inflicting an important percent of visits to dermatologists, basic care physicians, and allergists. regardless of a lot present learn curiosity, the pathophysiology of those issues and their optimal remedy stay doubtful. In Atopic Dermatitis & Eczematous issues, the

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Extra info for Atopic Dermatitis and Eczematous Disorders

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1988, Tupker et al. 1996). Other evidence to support the role of dust mite allergen in AD patients includes high titers of allergen Der1-specific IgE antibody in most atopic eczema patients (Colloff 1992), development of eczematous lesions after allergen patch testing, and the presence of mite allergens bound to Langerhans cells and Leu-3a-positive T cells after allergen patch testing AD skin (Tanaka Y et al. 1989). The lack of any clear exposure–disease relationship between allergens early in life and subsequent eczema argues against allergen exposure being a major factor causing AD.

The 31/10/13 9:18 PM The Epidemiology of Atopic Dermatitis relative role of hygiene, climate, or other factors that account for such geographical variation must be more firmly established. Furthermore, there tends to be a gradient between urban and rural areas within the same country. A clear urban/rural gradient has, for instance, been demonstrated in studies conducted in Sweden and the UK (Kjellman et al. 1982, NcNally and Phillips 2000). It remains unclear which environmental factors may be responsible for this urban/rural gradient.

2000). Another study showed that eczema severity was related to (1) disease onset during the first year of life, (2) concurrent occurrence of asthma, hayfever, or both, and (3) urban area habitation (Ben-Gashir et al. 2004), ie, factors that can indicate a worse prognosis include severe childhood disease, early onset, and concomitant or family history of asthma/hayfever (Popescu et al. 1998, Marks et al. 1999, Fung and Lo et al. 2000, Laughter et al. 2000, Yura and Shimizu 2001). Owing to logistics, few studies have quantified the morbidity of AD.

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Atopic Dermatitis and Eczematous Disorders by Donald Rudikoff, Steven R Cohen, Noah Scheinfeld


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