Jonathan A. Cotliar's Atlas of Graft-versus-Host Disease: Approaches to Diagnosis PDF

By Jonathan A. Cotliar

ISBN-10: 3319469509

ISBN-13: 9783319469508

ISBN-10: 3319469525

ISBN-13: 9783319469522

This atlas offers trainees and practising physicians a visible toolkit to aid realize and deal with this hard adequately. this article highlights the medical variability of GVHD, and palms readers with the diagnostic clues to categorize sufferers in line with the present grading/staging instructions. moreover, this atlas bargains evidence-based diagnostic and therapy algorithms for physicians to take advantage of whereas at sufferers' bedsides.

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Extra info for Atlas of Graft-versus-Host Disease: Approaches to Diagnosis and Treatment

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Chronic ocular graft versus host disease. In: Vogelsang GB, Pavletic SZ, editors. Chronic graft versus host disease: interdisciplinary management. New York: Cambridge University Press; 2009.  199–206.  Chronic cicatrizing conjunctivitis. Curr Opin Ophthalmol. 2001;12:250–7. host disease with severe cicatrizing conjunctivitis mimicking cicatricial pemphigoid. Br J Dermatol. 2000;143:209–10.  The role of medications in causing dry eye. J Ophthalmol. 2012;2012:285851. Methodologies to diagnose and monitor dry eye disease: report of the Diagnostic Methodology Subcommittee of the International Dry Eye WorkShop (2007).

B, c) Pseudomembranous ulcerations in chronic GVHD occur in many forms, and may eventually lose their pseudomembranous covering. Common sites include the base of the ventral tongue and the buccal mucosa. (d) Chronic GVHD may present on the cutaneous lip as wide, irregularly shaped ulcers in the setting of white lacy lesions, chapping, or generalized superficial hyperkeratosis of the cutaneous lip. (e) Ulcerations on the cutaneous lip may also be caused by viruses, including herpes simplex virus (HSV).

11 Morbilliform lesions on the chest and abdomen 3 Clinical Presentation of Acute Cutaneous Graft-Versus-Host Disease Erythroderma 25 Reticulated Patterns Erythrodermic aGVHD presents with confluent erythema- Acute GVHD may present in a reticulated, netlike pattern tous patches that mimic severe viral exanthema, drug reac- (Fig. 15). tions, psoriasis, eczematous dermatitis, cutaneous T-cell lymphoma, or staphylococcal scalded skin syndrome (SSSS) (Fig. 14). When mucous membrane lesions are present, there are no clinical or histologic differences between skin stage 4 aGVHD and toxic epidermal necrolysis (TEN) [7–9].

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Atlas of Graft-versus-Host Disease: Approaches to Diagnosis and Treatment by Jonathan A. Cotliar


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