Read e-book online An atlas of hair pathology with clinical correlations PDF

By Leonard C Sperling

ISBN-10: 1081111151

ISBN-13: 9781081111151

ISBN-10: 184184733X

ISBN-13: 9781841847337

ISBN-10: 1841847348

ISBN-13: 9781841847344

Diagnosing and treating hair problems continues to be a topic that's hardly or merely superficially coated in residency education. accordingly, dermatopathologists and scientific dermatologists frequently discover a hole of their wisdom. a brand new variation of an acclaimed textual content, An Atlas of Hair Pathology with medical Correlations, moment Edition bridges this hole and serves as a primer, an atlas, and a reference.

Features:

  • Supplies simple details on anatomy
  • Examines medical gains that offer a scientific / pathological correlation
  • Details the sensible methods of comparing specimens
  • Includes new images demonstrating uncomplicated and complex histologic beneficial properties of hair disease
  • Explores numerous new diagnoses

Disorders during this variation comprise senescent balding, unfastened anagen hair syndrome, psoriatic alopecia, and psoriatic alopecia, and chemotherapy-induced alopecia. The ebook additionally features a thesaurus of phrases relating to hair pathology.

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Additional info for An atlas of hair pathology with clinical correlations

Example text

However, as a starting point we use a four-step technique based on the answers to four histological questions: 1. Is the total number of hairs normal or reduced? 2. Is the overall size of hairs (on average) normal or reduced? 3. Is the telogen count (percentage of total terminal telogen hairs) normal or increased? 4. Is there a significant amount of inflammation present? Arriving at an answer to these four questions can narrow the histological differential diagnosis considerably, and sometimes the exact diagnosis may be obvious at this point.

Sullivan JR, Kossard S. Acquired scalp alopecia. Part I: a review. Australas J Dermatol. 1998; 39: 207–19; quiz 220–201. 5. Olsen E, Stenn K, Bergfeld W, et al. Update on cicatricial alopecia. J Investig Dermatol Symp Proc. 2003; 8: 18–19. 6. Olsen EA, Bergfeld WF, Cotsarelis G, et al. Summary of North American Hair Research Society (NAHRS)-sponsored Workshop on Cicatricial Alopecia, Duke University Medical Center, February 10 and 11, 2001. J Am Acad Dermatol. 2003; 48: 103–10. 7. Pincus LB, Price VH, McCalmont TH.

The work that followed focused on the conversion of testosterone to dihydrotestosterone (DHT) by the enzyme 5α-reductase type II (5αR-II) (13). Hair follicles of men and women with AGA have increased levels of 5αR-II (6). DHT formed from the action of 5αR-II on testosterone binds to the androgen receptor (AR) located in the outer root sheath and follicular papillae of hair follicles (14,15). The hormone–receptor complex then activates genes responsible for the gradual transformation of large, terminal follicles to small, miniaturized ones (6).

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An atlas of hair pathology with clinical correlations by Leonard C Sperling


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