By I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher F. Higgins
ABC Proteins is an in-depth, updated research of all that's identified in regards to the topic up to now. It discusses and compares evolution, biology and mechanism of motion of all recognized ABC proteins, together with the 1st structural reviews in addition to medical implications. it is going to be beneficial to a person attempting to remain abreast of the newest findings. This ebook is certain to turn into a vintage and may usually be up to date. Key positive factors* Phylogeny and Evoloution of ABC Transporters* basic elements of the Mechanism of motion of ABC Transporters* Prokaryote ABC Transporters* Non-Mammalian Transporters* Multidrug Transporters* ABC Transporters, Physiological Roles and Human disorder* complete colour all through
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Extra info for ABC Proteins: From Bacteria to Man
Interestingly, the IM and the SSA proteins of an MKL family system in M. tuberculosis have been subjected to extensive gene duplications, so that eight genes for IMs and ten genes for SSA proteins were identified in the genome. , 1993). It is therefore tempting to speculate that MKL systems are implicated in the maintenance of bacterial outer cell surface integrity. MKL systems are apparently not restricted to prokaryotes since a typical system was found in the nuclear genome of A. thaliana. The ABCY family Systems of the ABCY family have an overall organization similar to that of BPD transporters with the difference that the extracytoplasmic protein is a lipoprotein (LPP), even in Gram-negative bacteria.
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ABC Proteins: From Bacteria to Man by I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher F. Higgins
Categories: Basic Science